56 documents found
Article / Chapter
CC BY 4.0
2024
Protective MVA-ST vaccination robustly activates T cells and antibodies in an aged-hamster model for COVID-19
aus: Vaccines
Aging is associated with a decline in immune system functionality. So-called immunosenescence may impair the successful vaccination of elderly people. Thus, improved vaccination strategies also suitable for an aged immune system are required. Modified Vaccinia virus Ankara (MVA) is a highly attenuated…
Basel: MDPI, 2024
Poster / Abstract
All rights reserved
2024
Verteilung und Expressionsprofil pulmonaler neuroendokriner Zellen in der Lunge von Goldhamstern (Mesocricetus auratus) :…
Stuttgart: Thieme, 2024
Article / Chapter
CC BY 4.0
2024
Filamentous fungus-produced human monoclonal antibody provides protection against SARS-CoV-2 in hamster and non-human primate…
Monoclonal antibodies are an increasingly important tool for prophylaxis and treatment of acute virus infections like SARS-CoV-2 infection. However, their use is often restricted due to the time required for development, variable yields and high production costs, as well as the need for adaptation to…
London: Nature Publishing Group UK, 2024
Article / Chapter
CC BY 4.0
2024
Persistence of infectious canine distemper virus in murine xenotransplants of canine histiocytic sarcoma cells after intratumoral…
Oncolytic viruses and morbilliviruses in particular, represent an interesting therapeutic approach for tumors with a poor prognosis and frequent resistance to conventional therapies. Canine histiocytic sarcomas (HS) exemplify such a neoplasm in need for new curative approaches. Previous investigations…
Basel: Molecular Diversity Preservation International, 2024
Poster / Abstract
All rights reserved
2023
Pathologie der Retina bei COVID-19 Tiermodellen
Stuttgart: Thieme, 2023
Poster / Abstract
All rights reserved
2023
CK8+ alveolar intermediate differentiation cells are features of alveolar regeneration in SARS-CoV-2 infected hamsters
Stuttgart: Thieme, 2023
Poster / Abstract
All rights reserved
2023
Einfluss einer persistierenden Infektion mit dem kaninen Staupevirus (CDV) auf kanine histiozytäre Sarkomzellen
Stuttgart: Thieme, 2023
Poster / Abstract
All rights reserved
2023
CK8+ alveolar intermediate differentiation cells are features of alveolar regeneration in SARS-CoV-2 infected hamsters
Stuttgart: Thieme, 2023
Poster / Abstract
All rights reserved
2023
CK8+ alveolar intermediate differentiation cells are features of alveolar regeneration in SARS-CoV-2 infected hamsters
Stuttgart: Thieme, 2023
Poster / Abstract
All rights reserved
2023
Pathologie der Retina bei COVID-19 Tiermodellen
Stuttgart: Thieme, 2023
Poster / Abstract
All rights reserved
2023
Pathologie der Retina bei COVID-19 Tiermodellen
Stuttgart: Thieme, 2023
Poster / Abstract
All rights reserved
2023
Einfluss einer persistierenden Infektion mit dem kaninen Staupevirus (CDV) auf kanine histiozytäre Sarkomzellen
Stuttgart: Thieme, 2023
Poster / Abstract
All rights reserved
2023
Multipotente Basalzellen aus den terminalen Bronchiolen unterstützen die alveoläre Regeneration nach SARS-CoV-2 Infektion…
Stuttgart: Thieme, 2023
Article / Chapter
All rights reserved
2023
Vulvo-vaginal epithelial tumors in mares : a preliminary investigation on epithelial-mesenchymal transition and tumor-immune…
aus: Veterinary pathology
Vulvo-vaginal epithelial tumors are uncommon in mares, and data on the epithelial-to-mesenchymal transition (EMT) and the tumor-immune microenvironment (TIME) are still lacking. This is a study investigating the equus caballus papillomavirus type 2 (EcPV2) infection state as well as the EMT process and…
London: SAGE, 2023
Article / Chapter
CC BY 4.0
2023
Hamster model for post-COVID-19 alveolar regeneration offers an opportunity to understand post-acute sequelae of SARS-CoV-2
COVID-19 survivors often suffer from post-acute sequelae of SARS-CoV-2 infection (PASC). Current evidence suggests dysregulated alveolar regeneration as a possible explanation for respiratory PASC, which deserves further investigation in a suitable animal model. This study investigates morphological,…
London: Nature Publishing Group UK, 2023
Article / Chapter
CC BY 4.0
2023
MEK1/2 regulate normal BCR and ABL1 tumor-suppressor functions to dictate ATO response in TKI-resistant Ph+ leukemia
Resistance to tyrosine kinase inhibitors (TKIs) remains a clinical challenge in Ph-positive variants of chronic myeloid leukemia. We provide mechanistic insights into a previously undisclosed MEK1/2/BCR::ABL1/BCR/ABL1-driven signaling loop that may determine the efficacy of arsenic trioxide (ATO) in…
London: Springer Nature, 2023
Poster / Abstract
All rights reserved
2022
Ermittlung der Empfänglichkeit von Feliden für SARS-CoV-2 Infektionen anhand von primären Zellkultursystemen
Stuttgart: Thieme, 2022
Poster / Abstract
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2022
Empfänglichkeit von ex vivo und in vitro-Kultursystemen von verschiedenen Tierarten für SARS-CoV2
Stuttgart: Thieme, 2022
Poster / Abstract
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2022
Ein seltener Fall bei einer gefährdeten Tierart: malignes epitheloides Mesotheliom beim Prinz-Alfred-Hirsch (Cervus alfredi)
Stuttgart: Thieme, 2022
Article / Chapter
CC BY 4.0
2022
Stabilized recombinant SARS-CoV-2 spike antigen enhances vaccine immunogenicity and protective capacity
The SARS-CoV-2 spike (S) glycoprotein is synthesized as a large precursor protein and must be activated by proteolytic cleavage into S1 and S2. A recombinant modified vaccinia virus Ankara (MVA) expressing native, full-length S protein (MVA-SARS-2-S) is currently under investigation as a candidate vaccine…
Ann Arbor, Mich.: American Society for Clinical Investigation, 2022