Stiftung Tierärztliche Hochschule Hannover (TiHo)TiHo eLib

Expression of neuroectodermal markers in atypical fibromas in two dwarf hamsters (Phodopus spp.)

Affiliation
Department of Pathology, University of Veterinary Medicine, Hannover, Germany.
Pertl, Katharina;
Affiliation
Clinic of Small Animals Herrenhausen, Hannover, Germany.
Borchers, M.;
GND
142929565
ORCID
0000-0001-8151-5644
Affiliation
Department of Pathology, University of Veterinary Medicine, Hannover, Germany.
Baumgärtner, Wolfgang;
ORCID
0000-0001-9184-4134
Affiliation
Department of Pathology, University of Veterinary Medicine, Hannover, Germany. Electronic address: peter.wohlsein@tiho-hannover.de.
Wohlsein, Peter

A 2-year-old male Djungarian hamster (Phodopus sungorus) and a 1-year-old male Roborovski hamster (Phodopus roborovskii) were presented with expansile subcutaneous masses. The well-demarcated, firm, grey, multilobulated nodules displayed an homogeneous, white-grey cut surface. Histological examination revealed a neoplasm of variable cellularity consisting of spindle-shaped to polygonal 'ganglion cell-like' cells with abundant, amphophilic, vacuolated cytoplasm. Immunohistochemically, the tumour cells were labelled intensely for vimentin and nestin, moderately for neuron specific enolase and weakly for melan-A. The histological and immunohistochemical findings were suggestive of an atypical fibroma with evidence of a neuroectodermal phenotype.

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