Stiftung Tierärztliche Hochschule Hannover (TiHo)

Expression of neuroectodermal markers in atypical fibromas in two dwarf hamsters (Phodopus spp.)

Pertl, Katharina; Borchers, M.; Baumgärtner, Wolfgang GND; Wohlsein, Peter ORCID

A 2-year-old male Djungarian hamster (Phodopus sungorus) and a 1-year-old male Roborovski hamster (Phodopus roborovskii) were presented with expansile subcutaneous masses. The well-demarcated, firm, grey, multilobulated nodules displayed an homogeneous, white-grey cut surface. Histological examination revealed a neoplasm of variable cellularity consisting of spindle-shaped to polygonal 'ganglion cell-like' cells with abundant, amphophilic, vacuolated cytoplasm. Immunohistochemically, the tumour cells were labelled intensely for vimentin and nestin, moderately for neuron specific enolase and weakly for melan-A. The histological and immunohistochemical findings were suggestive of an atypical fibroma with evidence of a neuroectodermal phenotype.

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Pertl, K. / Borchers, M. / Baumgärtner, W. / et al: Expression of neuroectodermal markers in atypical fibromas in two dwarf hamsters (Phodopus spp.). 2019.

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