Neurobiology of disease

Contentshow allhide all

1. 2025

   • Vol. 210: Sinbaglustat ameliorates disease pathology in a murine model of GM1 gangliosidosis without affecting CNS ganglioside levels

     Wannemacher, Rouven; Jubran-Rudolf, Lorna; Zdora, Isabel; Leitzen, Eva; Rohn, Karl; Sippel, Virginie; Paschen, Christoph; Blattmann, Peter; Baumgärtner, Wolfgang; Gerhauser, Ingo; Steiner, Michel Alexander

   • Vol. 205: Alpha-synuclein pathology enhances peripheral and CNS immune responses to bacterial endotoxins

     Hartke, Anna-Sophia; Schreiber, Cara S.; Lau, Kristina; Wiesweg, Ivo; Waltl, Inken; Kalinke, Ulrich; Richter, Franziska; Käufer, Christopher
2. 2023

   • Vol. 187: Microvascular blood-brain barrier alterations in isolated brain capillaries of mice over-expressing alpha-synuclein (Thy1-aSyn line 61)

     Lau, Kristina; Porschen, Lisa Teresa; Richter, Franziska; Gericke, Birthe

   • Vol. 187: Long-lasting antiseizure effects of chronic intrasubthalamic convection-enhanced delivery of valproate

     MacKeigan, Devlin; Feja, Malte; Meller, Sebastian; Deking, Lillian; Javadova, Amina; Veenhuis, Alva; Felmy, Felix; Gernert, Manuela
3. 2021

   • Vol. 149: 105227: Systematic evaluation of rationally chosen multitargeted drug combinations : a combination of low doses of levetiracetam, atorvastatin and ceftriaxone exerts antiepileptogenic effects in a mouse model of acquired epilepsy

     Welzel, Lisa; Bergin, David H.; Schidlitzki, Alina; Twele, Friederike; Johne, Marie; Klein, Pavel; Löscher, Wolfgang

   • Vol. 158: Scopolamine prevents aberrant mossy fiber sprouting and facilitates remission of epilepsy after brain injury

     Meller, Sebastian; Käufer, Christopher; Gailus, Björn; Brandt, Claudia; Löscher, Wolfgang

   • Vol. 152: 105297: Deletion of the Na-K-2Cl cotransporter NKCC1 results in a more severe epileptic phenotype in the intrahippocampal kainate mouse model of temporal lobe epilepsy

     Hampel, Philip; Johne, Marie; Gailus, Björn; Vogel, Alexandra; Schidlitzki, Alina; Gericke, Birthe; Töllner, Kathrin; Theilmann, Wiebke; Käufer, Christopher; Römermann, Kerstin; Kaila, Kai; Löscher, Wolfgang

   • Vol. 158: Alpha-synuclein pathology, microgliosis, and parvalbumin neuron loss in the amygdala associated with enhanced fear in the Thy1-aSyn model of Parkinson's disease

     Torres, Eileen Ruth S.; Stanojlovic, Milos; Zelikowsky, Moriel; Bonsberger, Jana; Hean, Sindalana; Mulligan, Caitlin; Baldauf, Leonie; Fleming, Sheila; Masliah, Eliezer; Chesselet, Marie-Francoise; Fanselow, Michael S.; Richter, Franziska
4. 2020

   • Vol. 134: Proof-of-concept that network pharmacology is effective to modify development of acquired temporal lobe epilepsy

     Schidlitzki, Alina; Bascuñana, Pablo; Srivastava, Prashant K.; Welzel, Lisa; Twele, Friederike; Töllner, Kathrin; Käufer, Christopher; Gericke, Birthe; Feleke, Rahel; Meier, Martin; Polyak, Andras; Ross, Tobias L.; Gerhauser, Ingo; Bankstahl, Jens P.; Johnson, Michael R.; Bankstahl, Marion; Löscher, Wolfgang

   • Vol. 143: Disruption of the sodium-dependent citrate transporter SLC13A5 in mice causes alterations in brain citrate levels and neuronal network excitability in the hippocampus

     Henke, Christine; Töllner, Kathrin; van Dijk, R. Maarten; Miljanovic, Nina; Cordes, Thekla; Twele, Friederike; Bröer, Sonja; Ziesak, Vanessa; Rohde, Marco; Hauck, Stefanie M.; Vogel, Charlotte; Welzel, Lisa; Schumann, Tina; Willmes, Diana M.; Kurzbach, Anica; El-Agroudy, Nermeen N.; Bornstein, Stefan R.; Schneider, Susanne A.; Jordan, Jens; Potschka, Heidrun; Metallo, Christian M.; Köhling, Rüdiger; Birkenfeld, Andreas L.; Löscher, Wolfgang
5. 2019

   • Vol. 130: Attenuation of epileptogenesis by 2-deoxy-d-glucose is accompanied by increased cerebral glucose supply, microglial activation and reduced astrocytosis

     Leiter, Ina; Bascuñana, Pablo; Bengel, Frank Michael; Bankstahl, Jens Peter; Bankstahl, Marion

   • Vol. 124: Changes of dimension of EEG/ECoG nonlinear dynamics predict epileptogenesis and therapy outcomes

     p. 373

     Rizzi, Massimo; Brandt, Claudia; Weissberg, Itai; Milikovsky, Dan Z; Pauletti, Alberto; Terrone, Gaetano; Salamone, Alessia; Frigerio, Federica; Löscher, Wolfgang; Friedman, Alon; Vezzani, Annamaria