Neurobiology of disease

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1. 2021

   • 149: 105227 - Systematic evaluation of rationally chosen multitargeted drug combinations: a combination of low doses of levetiracetam, atorvastatin and ceftriaxone exerts antiepileptogenic effects in a mouse model of acquired epilepsy

     Welzel, Lisa; Bergin, David H.; Schidlitzki, Alina; Twele, Friederike; Johne, Marie; Klein, Pavel; Löscher, Wolfgang

   • 152: 105297 - Deletion of the Na-K-2Cl cotransporter NKCC1 results in a more severe epileptic phenotype in the intrahippocampal kainate mouse model of temporal lobe epilepsy

     Hampel, Philip; Johne, Marie; Gailus, Björn; Vogel, Alexandra; Schidlitzki, Alina; Gericke, Birthe; Töllner, Kathrin; Theilmann, Wiebke; Käufer, Christopher; Römermann, Kerstin; Kaila, Kai; Löscher, Wolfgang
2. 2020

   • 134: 104664 - Proof-of-concept that network pharmacology is effective to modify development of acquired temporal lobe epilepsy

     Schidlitzki, Alina; Bascuñana, Pablo; Srivastava, Prashant K; Welzel, Lisa; Twele, Friederike; Töllner, Kathrin; Käufer, Christopher; Gericke, Birthe; Feleke, Rahel; Meier, Martin; Polyak, Andras; Ross, Tobias L; Gerhauser, Ingo; Bankstahl, Jens P; Johnson, Michael R; Bankstahl, Marion; Löscher, Wolfgang

   • 143: 105018 - Disruption of the sodium-dependent citrate transporter SLC13A5 in mice causes alterations in brain citrate levels and neuronal network excitability in the hippocampus

     Henke, Christine; Töllner, Kathrin; van Dijk, R Maarten; Miljanovic, Nina; Cordes, Thekla; Twele, Friederike; Bröer, Sonja; Ziesak, Vanessa; Rohde, Marco; Hauck, Stefanie M; Vogel, Charlotte; Welzel, Lisa; Schumann, Tina; Willmes, Diana M; Kurzbach, Anica; El-Agroudy, Nermeen N; Bornstein, Stefan R; Schneider, Susanne A; Jordan, Jens; Potschka, Heidrun; Metallo, Christian M; Köhling, Rüdiger; Birkenfeld, Andreas L; Löscher, Wolfgang
3. 2019

   • 130 - Attenuation of epileptogenesis by 2-deoxy-d-glucose is accompanied by increased cerebral glucose supply, microglial activation and reduced astrocytosis

     Leiter, Ina; Bascuñana, Pablo; Bengel, Frank Michael; Bankstahl, Jens Peter; Bankstahl, Marion

   • 124 - Changes of dimension of EEG/ECoG nonlinear dynamics predict epileptogenesis and therapy outcomes

     p. 373

     Rizzi, Massimo; Brandt, Claudia; Weissberg, Itai; Milikovsky, Dan Z; Pauletti, Alberto; Terrone, Gaetano; Salamone, Alessia; Frigerio, Federica; Löscher, Wolfgang; Friedman, Alon; Vezzani, Annamaria