Effekte einer chronischen Behandlung mit dem ACE-Inhibitor Ramipril, dem ACE/NEP-Inhibitor AVE 7688 sowie in Kombination mit dem B2-Rezeptor-Antagonisten HOE 140 in adulten diabetischen und nicht-diabetischen Ratten

Hahn, Alexandra

Published

Effekte einer chronischen Behandlung mit dem ACE-Inhibitor Ramipril, dem ACE/NEP-Inhibitor AVE 7688 sowie in Kombination mit dem B2-Rezeptor-Antagonisten HOE 140 in adulten diabetischen und nicht-diabetischen Ratten

According to WHO estimates, approximately 177 million people, worldwide, suffer from diabetes at the present time. WHO predicts that this number will likely double by the year 2025. Of these diabetics, approximately 90% will have type 2 diabetes. Diabetes is a disease characterised by complications, and leads to damage of the vascular system and critical organs, particularly the kidneys and the heart. This study examined the pharmacological effects of ACE and ACE/NEP inhibitors, both individually as well as in combination with a B2 receptor antagonist, in adult diabetic ...